Doublecortin anticorps (AA 413-417)

N° du produit ABIN5689407

Cet anticorps Lapin Polyclonal détecte spécifiquement Doublecortin dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Doublecortin anticorps (AA 413-417) (ABIN5689407)

Antigène: Doublecortin (DCX)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Doublecortin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Doublecortin anticorps

Épitope: AA 413-417

Specificité: This antibody detects endogenous level of total Doublecortin protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Doublecortin antibody was raised against a peptide sequence around aa.413~417 ( P-T-S-P-G) derived from Human Doublecortin.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur Doublecortin

Antigène: Doublecortin (DCX)

Autre désignation: Doublecortin

Sujet: Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.

Poids moléculaire: 40 - 45 kDa

ID gène: 1641

NCBI Accession: NP_000546

UniProt: O43602